Marie-Claude Vohl completed her graduate studies at Laval University from 1992 to 1997. She was interested in the genetics of dyslipidemia and obesity-related metabolic complications. In 1997-1998, she was enrolled in a post-doctoral fellow at the University of Ottawa Heart Institute where she studied antioxidant properties of HDL. During her second post-doctoral training (1998-1999) at McGill University in Montreal, she was interested in the genetics of complex disorders. She has been appointed as a professor at the Department of Food Science and Nutrition at Laval University (Quebec City) in 1999. Her research projects are aimed at the genetic dissection of the atherogenic dyslipidemia of abdominally obese/insulin-resistant men. She is also interested in nutrigenetics/nutrigenomics. She conducted different cross-sectional and intervention studies examining the combined effects of dietary fat and genetic factors on cardio-vascular disease risk factors.
Since the beginning of her career, Marie-Claude Vohl has published more than 100 peer-reviewed articles. She has been invited to give several presentations in national and international conferences. Her research programs are funded from CIHR, CDA, FRSQ and other granting agencies. She also acts on review committees for different Canadian granting agencies.
Paradis, A.-M., Godin, G., Lemieux, S., Pérusse, L., Vohl, M.-C. (2009) "Eating behaviors of non-obese individuals with and without familial history of obesity" British Journal of Nutrition 101(7): 1103-9.
Paradis, A.-M., Godin, G., Pérusse, L., Vohl, M.-C. (2009) "Interaction between familial history of obesity and fat intakes on obesity phenotypes" Journal of Nutrigenetics and Nutrigenomics 2(1): 37-42.
Rudkowska, I., Verreault, M., Barbier, O., Vohl, M.-C. (2009) "Differences in transcriptional activation by the two Allelic (L162V polymorphic) variants of PPARα after omega-3 fatty acids treatment" PPAR Research (in press).
2008
Caron-Dorval, D., Paquet, P., Paradis, A.-M., Rudkowska, I., Lemieux, S., Couture, P., Vohl, M.-C. (2008) "Effect of the PPAR-alpha L162V polymorphism on the cardiovascular disease risk factor in response to n-3 PUFA" Journal of Nutrigenetics and Nutrigenomics 1(4): 205-12.
Choquette, A.C., Lemieux, S., Tremblay, A., Chagnon, Y.C., Bouchard, C., Vohl, M.-C., Pérusse, L. (2008) "Evidence of a quantitative trait locus for energy and macronutrient intake on chromosome 3q27.3 in the Quebec Family Study" American Journal of Clinical Nutrition 8(4): 1142-8.
2007
Robitaille, J., Gaudet, D., Pérusse, L., Vohl, M.-C. (2007) "Features of the metabolic syndrome are modulated by an interaction between the PPAR-delta -87T>C polymorphism and dietary fat in French-Canadians" International Journal of Obesity 31(3): 411-17.
Robitaille, J., Houde, A., Lemieux, S., Gaudet, D., Pérusse, L., Vohl, M.-C. (2007) "The lipoprotein/lipid profile is modulated by a gene-diet interaction effect between polymorphisms in the Liver X Receptor-alpha and dietary cholesterol intake in French-Canadians" The British Journal of Nutrition 97(1): 11-18.
Robitaille, J., Houde, A., Lemieux, S., Pérusse, L., Gaudet, D., Vohl, M.-C. (2007) "Variants within the muscle and liver isoforms of the Carnitine Palmitoyltransferase I (CPT1) gene interact with fat intake to modulate indices of obesity in French-Canadians" Journal of Molecular Medicine 85(2): 129-37.
Robitaille, J., Pérusse, L., Bouchard, C., Vohl, M.C. (2007) "Genes, fat intake and cardiovascular disease risk factors: a study of gene-diet interactions in the Quebec Family Study" Obesity 15(9): 2336-47.
Zhang, Y., Bossé, Y., Marceau, P., Biron, S., Lebel, S., Richard, D., Vohl, M.-C., Tchernof, A. (2007) "Gene expression variability in subcutaneous and omental adipose tissue of obese men" Gene Expression 14(1): 35-46.
2006
Paradis, A.-M., Pérusse, L., Vohl, M.-C. (2006) "Dietary patterns and associated lifestyles in individuals with and without familial history of obesity : A cross-sectional studies" International Journal of Behavioral Nutrition and Physical Activity 3: 38.
Robitaille, J., Vohl, M.-C. (2006) «Nutrigénomique: la génomique au service de la nutrition» Revue de l’Ordre professionnel des diététistes du Québec: Nutrition - science en évolution 4(1): 19-23.
2005
Paradis, A.-M., Fontaine-Bisson, B., Bossé, Y., Robitaille, J., Lemieux, S., Jacques, H., Lamarche, B., Tchernof, A., Couture, P., Vohl, M.-C. (2005) "The peroxisome proliferator-activated receptor alpha Leu162Val polymorphism influences the metabolic response to a dietary intervention altering fatty acid proportions in healthy men" American Journal of Clinical Nutrition 81(2): 523-30.
Robitaille, J., Brouillette, C., Houde, A., Lemieux, S., Pérusse, L., Tchernof, A., Gaudet, D., Vohl, M.-C. (2004) "Association between the PPARα-L162V polymorphism and components of the metabolic syndrome" Journal of Human Genetics 49(9): 482-89.
Robitaille, J., Brouillette, C., Lemieux, S., Pérusse, L., Gaudet, D., Vohl, M.-C. (2004) "Plasma concentrations of apoprotein B are modulated by a gene-diet interaction effect between the LFABP T94A polymorphism and dietary fat intake in French-Canadian men" Molecular Genetics & Metabolism 82(4): 296-303.
2003
Paradis, M.-E., Couture, P., Bossé, Y., Després, J.-P., Pérusse, L., Bouchard, C., Vohl, M.-C., Lamarche, B. (2003) "The T111I missense mutation of the endothelial lipase gene modulates the relationship between dietary fat intake and the HDL profile in women" Journal of Lipid Research 44(10): 1902-8.
Robitaille, J., Després, J.-P., Pérusse, L., Vohl, M.-C. (2003) "The PPAR-gamma P12A polymorphism modulates the relation between dietary fat intake and components of the metabolic syndrome: Results from the Québec Family Study" Clinical Genetics 63(2): 109-16.
We updated our literature reviews in the fields of ethics & nutrigenomics, public health genomics, pharmacogenomics, human enhancement, and the genetics of brain disorders. Click on a research area icon (on the main page) and select the... Read more
We updated our literature reviews in the fields of ethics & nutrigenomics, public health genomics, pharmacogenomics, human enhancement, and the genetics of brain disorders. Click on a research area icon (on the main page) and select the section "Related material" to consult our selections of references.
Cont@ct Marie-Claude Vohl